Sensitive and all-around

Explore the frontier of drug discovery with our cutting-edge assay platform, featuring GPCR-selective signal amplification technology and unparalleled receptor coverage.

Welcome to Tanso Biosciences, a specialized provider of functional assays for G-protein-coupled receptors (GPCRs). Our technology enables sensitive evaluation of GPCR-induced signals in proprietary reporter cells, offering specific readouts across various animal species, including humans, mice, rats, rabbits, dogs, and macaque monkeys. We provide customized assays for pharmaceuticals, biotech companies, food companies, and academia globally. Additionally, we conduct in-house drug discovery projects. Explore our site to learn more about our services and how we can support your research.

Core Business

Drug Discovery Enterprise

We take advantage of our all-around assay technology and engage in drug discovery for orphan GPCRs.

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Contract Services

Panel assays, concentration dependence analysis, and other functional assays for > 550 human and mouse GPCRs.

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Key Features

Potency-Oriented

Characterizes compounds' potency, not affinity, on the G-protein pathways of the target GPCR in various modes

Super-Sensitive

Dramatically and specifically amplifies G-protein-dependent signals

All-Around

All GPCRs are amenable in single assay format, regardless of Gα proteins coupled or even animal species

Assay Platform

Uses

compass
  • On-target and off-target screening for drug discovery
  • Cross-species comparison
  • Compound profiling, structure-activity relationship (SAR) analysis
  • In-licensing assessment
  • Drug repurposing

Assay Examples

Shown below are a few use cases of our assay platform.

Large-Scale Panel

Antagonistic activities of carvedilol against 200 human non-orphan GPCRs

Conc-Response Analysis

AGTR1 was treated with various concentrations of an antagonist, valsartan, in the presence of angiotensin II.

Inter-Species Analysis

Human and mouse GPCRs were treated with their agonists/antagonists.

Orphan GPCR Screening

Concentration-dependent activation of GPR68 by a newly identified agonist

Proton Sensitivity

Activity of GPR65 at various pH

G12/13

Agonist-induced concentration-dependent activation of LPAR6, a G12/13-coupled receptor

Clients & Partners

Here are just a few of our valued clients and partners.

Testimonials

I highly recommend Tanso Biosciences for their assay platform. Its reliability and industry-leading receptor coverage make it a uniquely valuable guide to GPCR drug discovery. We experienced a quick turnaround time as well.

KEN HORNE
CEO, Capacity Bio, CA, USA

Tanso Bio helps us accelerate structure-activity relationship studies.

Researcher, Pharma A

Tanso Bio's assays have revealed key features of our compounds that would otherwise remain unnoticed.

Researcher, Pharma B

News & Updates

News
GPCR Safety Panels Launched
Web Updates
New Assay Results
News
Core Technology for Our GPCR Functional Assay Patented in Japan
News
HiRAKU GATE
Office Relocated
Resources
長岡の花火
Reproducibility of Tanso Biosciences' GPCR Assay
News
Tokyo skyline view. tanso Biosciences has been awarded a grant for technological innovation by the Government of Tokyo.
Tanso Awarded Grant for Technological Innovation

Contact Us

Send us a message via the form below or write to us at [email protected].

Ordering Process

Service flow chart

Request a quotation

We hear about the study outline and propose experiments. A non-disclosure agreement is optional.

STEP
1

Place an order

You place an order, ship your compounds to our lab, and pay the fee via bank transfer or by credit card.

STEP
2

Wait

The turnaround time can be as short as two weeks, depending on the study scale and design and the backlog of orders.

STEP
3

Receive the report

You receive the study report in PDF.

STEP
4

Inquiry & RFQ Form