Bradykinin receptors - Tanso Biosciences

Overview

Bradykinin (or kinin) receptors are activated by the endogenous peptides bradykinin (BK), [des-Arg⁹]bradykinin, Lys-BK (kallidin), [des-Arg¹⁰]kallidin, [Phospho-Ser⁶]-Bradykinin, T-kinin (Ile-Ser-BK), [Hyp³]bradykinin and Lys-[Hyp³]-bradykinin. Variation in pharmacology and activity of B₁... [read more] and B₂ receptor antagonists at species orthologs has been documented. icatibant (Hoe140, Firazir) is approved in North America and Europe for the treatment of acute attacks of hereditary angioedema. [close]


Human	BDKRB1 bradykinin receptor B1
Human	BDKRB2 bradykinin receptor B2

Human

BDKRB1

bradykinin receptor B1

Human

BDKRB2

bradykinin receptor B2

Species	Receptor	Family	Assays
Human	BDKRB1 bradykinin receptor B1	Bradykinin receptors	Assay modes: - Panels: -	Reference agonist: EC50:
Human	BDKRB2 bradykinin receptor B2	Bradykinin receptors	Assay modes: - Panels: -	Reference agonist: EC50:

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