Neuropeptide FF/neuropeptide AF receptors

Overview

The Neuropeptide FF receptor family contains two subtypes, NPFF1 and NPFF2, which exhibit high affinities for neuropeptide FF (NPFF, O15130) and RFamide related peptides (RFRP: precursor gene symbol... [read more] NPVF, Q9HCQ7). NPFF1 is broadly distributed in the central nervous system with the highest levels found in the limbic system and the hypothalamus. NPFF2 is present in high density in the superficial layers of the mammalian spinal cord where it is involved in nociception and modulation of opioid functions. [close]


Human	NPFFR1 neuropeptide FF receptor 1
Human	NPFFR2 neuropeptide FF receptor 2
Mouse	Npffr1 neuropeptide FF receptor 1
Mouse	Npffr2 neuropeptide FF receptor 2

Human

NPFFR1

neuropeptide FF receptor 1

Human

NPFFR2

neuropeptide FF receptor 2

Mouse

Npffr1

neuropeptide FF receptor 1

Mouse

Npffr2

neuropeptide FF receptor 2

Receptor	Family	Assays
NPFFR1	Neuropeptide FF/neuropeptide AF receptors	Available Assay modes: Agonist ⋅ Inverse agonist ⋅ Antagonist ⋅ PAM ⋅ NAM Panels: Human non-orphan GPCRs ⋅ à la carte
NPFFR2	Neuropeptide FF/neuropeptide AF receptors	Available Assay modes: Agonist ⋅ Inverse agonist ⋅ Antagonist ⋅ PAM ⋅ NAM Panels: Human non-orphan GPCRs ⋅ à la carte
Npffr1	Neuropeptide FF/neuropeptide AF receptors	Available Assay modes: Agonist ⋅ Inverse agonist ⋅ Antagonist ⋅ PAM ⋅ NAM Panels: Mouse non-orphan GPCRs ⋅ à la carte
Npffr2	Neuropeptide FF/neuropeptide AF receptors	Available Assay modes: Agonist ⋅ Inverse agonist ⋅ Antagonist ⋅ PAM ⋅ NAM Panels: Mouse non-orphan GPCRs ⋅ à la carte

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