Succinate receptor - Tanso Biosciences

Overview

The Succinate receptor was identified as being activated by physiological levels of the Kreb's cycle intermediate succinate and other dicarboxylic acids such as maleate in 2004. Since its pairing with... [read more] its endogenous ligand, the receptor has been the focus of intensive research and its role has been evidenced in various (patho)physiological processes such as regulation of renin production, retinal angiogenesis, inflammation or the immune response. [close]


Human	SUCNR1 succinate receptor 1
Mouse	Sucnr1 succinate receptor 1

Human

Mouse

Species	Receptor	Family	Assays
Human	SUCNR1 succinate receptor 1	Succinate receptor	Available Assay modes: Agonist ⋅ Inverse agonist ⋅ Antagonist ⋅ PAM ⋅ NAM Panels: Human non-orphan GPCRs ⋅ Ophthalmology ⋅ à la carte	Reference agonist: succinic acid EC50: 14 µM
Mouse	Sucnr1 succinate receptor 1	Succinate receptor	Available Assay modes: Agonist ⋅ Inverse agonist ⋅ Antagonist ⋅ PAM ⋅ NAM Panels: Mouse non-orphan GPCRs ⋅ à la carte	Reference agonist: succinic acid EC50:

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