Human HTR1A

Figure. Concentration-dependent activation of HTR1A by serotonin

Reporter cells were transfected with either the expression plasmid for human 5-hydroxytryptamine receptor 1A (HTR1A) or the mock plasmid and treated with various concentrations of serotonin. Data points shown are the mean ± SEM of an experiment (n = 3), and the curve is a fit to Hill equation with an EC50 of 13 nM.