Human HTR1B

Figure. Concentration-dependent activation of HTR1B by serotonin

Reporter cells were transfected with either the expression plasmid for human 5-hydroxytryptamine receptor 1B (HTR1B) or the mock plasmid and treated with various concentrations of serotonin. Data points shown are the mean ± SEM of an experiment (n = 3), and the curve is a fit to Hill equation with an EC50 of 4.0 nM.

Nomenclature
5-hydroxytryptamine receptor 1B
Available assay modes
Agonist, Inverse agonist, Antagonist, PAM, NAM
Panels
à la carte, Psychiatry, Neurology, Cardiology, Safety Premium, Safety, Human non-orphan GPCRs

HTR1B orthologs in other animal species including rat, rabbit, dog, and macaque monkey are ready upon request.

Related Receptors

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Human
HTR1A
5-hydroxytryptamine receptor 1A
Human
HTR1B
5-hydroxytryptamine receptor 1B
Human
HTR1D
5-hydroxytryptamine receptor 1D
Human
HTR1E
5-hydroxytryptamine receptor 1E
Human
HTR1F
5-hydroxytryptamine receptor 1F
Human
HTR2A
5-hydroxytryptamine receptor 2A
Human
HTR2B
5-hydroxytryptamine receptor 2B
Human
HTR2C
5-hydroxytryptamine receptor 2C
Human
HTR4
5-hydroxytryptamine receptor 4
Human
HTR5A
5-hydroxytryptamine receptor 5A
Human
HTR6
5-hydroxytryptamine receptor 6
Human
HTR7
5-hydroxytryptamine receptor 7
Mouse
Htr1a
5-hydroxytryptamine (serotonin) receptor 1A
Mouse
Htr1b
5-hydroxytryptamine (serotonin) receptor 1B
Mouse
Htr1d
5-hydroxytryptamine (serotonin) receptor 1D
Mouse
Htr1f
5-hydroxytryptamine (serotonin) receptor 1F
Mouse
Htr2a
5-hydroxytryptamine (serotonin) receptor 2A
Mouse
Htr2b
5-hydroxytryptamine (serotonin) receptor 2B
Mouse
Htr2c
5-hydroxytryptamine (serotonin) receptor 2C
Mouse
Htr4
5 hydroxytryptamine (serotonin) receptor 4
Mouse
Htr5a
5-hydroxytryptamine (serotonin) receptor 5A
Mouse
Htr6
5-hydroxytryptamine (serotonin) receptor 6
Mouse
Htr7
5-hydroxytryptamine (serotonin) receptor 7