cholinergic receptor muscarinic 3 (CHRM3)

Human CHRM3

Figure. Concentration-dependent activation of CHRM3 by carbachol

Reporter cells were transfected with either the expression plasmid for human cholinergic receptor muscarinic 3 (CHRM3) or the mock plasmid and treated with various concentrations of carbachol. Data points shown are the mean ± SEM of an experiment (n = 3), and the curve is a fit to Hill equation with an EC50 of 31 nM.

説明

Nomenclature: cholinergic receptor muscarinic 3
Available assay modes: Agonist, Inverse agonist, Antagonist, PAM, NAM
Panels: à la carte, Immunology/Infection, Hematology, Endocrinology/Metabolism, Psychiatry, Ophthalmology, Cardiology, Respiratory, Gastrointestinal, Dermatology, Musculoskeletal, Urology/Reproduction, Safety Premium, Safety, Human non-orphan GPCRs

CHRM3 orthologs in other animal species including rat, rabbit, dog, and macaque monkey are ready upon request.

Related Receptors


Human	CHRM1 cholinergic receptor muscarinic 1
Human	CHRM2 cholinergic receptor muscarinic 2
Human	CHRM3 cholinergic receptor muscarinic 3
Human	CHRM4 cholinergic receptor muscarinic 4
Human	CHRM5 cholinergic receptor muscarinic 5
Mouse	Chrm1 cholinergic receptor, muscarinic 1, CNS
Mouse	Chrm2 cholinergic receptor, muscarinic 2, cardiac
Mouse	Chrm3 cholinergic receptor, muscarinic 3, cardiac
Mouse	Chrm4 cholinergic receptor, muscarinic 4
Mouse	Chrm5 cholinergic receptor, muscarinic 5