Human ADRB3

Figure. Concentration-dependent activation of ADRB3 by isoproterenol

Reporter cells were transfected with either the expression plasmid for human adrenoceptor beta 3 (ADRB3) or the mock plasmid and treated with various concentrations of isoproterenol. Data points shown are the mean ± SEM of an experiment (n = 3), and the curve is a fit to Hill equation with an EC50 of 47 nM.

Nomenclature
adrenoceptor beta 3
Available assay modes
Agonist, Inverse agonist, Antagonist, PAM, NAM
Panels
à la carte, Endocrinology/Metabolism, Cardiology, Safety Premium, Human non-orphan GPCRs

ADRB3 orthologs in other animal species including rat, rabbit, dog, and macaque monkey are ready upon request.

Related Receptors

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