Human AGTR1

Figure 1. Concentration-dependent activation of AGTR1 by angiotensin ⅠⅠ

Reporter cells were transfected with either the expression plasmid for human angiotensin ⅠⅠ receptor type 1 (AGTR1) or the mock plasmid and treated with various concentrations of angiotensin ⅠⅠ. Data points shown are the mean ± SEM of an experiment (n = 3), and the curve is a fit to Hill equation with an EC50 of 920 pM.

Figures 2, 3. Concentration-dependent inhibition of AGTR1

Reporter cells were transfected with the expression plasmid for human AGTR1 and treated with various concentrations of an antagonist in the presence of angiotensin ⅠⅠ. Data points shown are the mean ± SEM of an experiment (n = 4).