Human CALCRL

Figure. Concentration-dependent activation of CALCRL by CGRP

Reporter cells were transfected with either the expression plasmid for human calcitonin receptor like receptor (CALCRL) or the mock plasmid and treated with various concentrations of CGRP. Data points shown are the mean ± SEM of an experiment (n = 3), and the curve is a fit to Hill equation with an EC50 of 1.0 nM.