Human CCR4

Figure. Concentration-dependent activation of CCR4 by CCL22

Reporter cells were transfected with either the expression plasmid for human C-C motif chemokine receptor 4 (CCR4) or the mock plasmid and treated with various concentrations of CCL22. Data points shown are the mean ± SEM of an experiment (n = 3), and the curve is a fit to Hill equation with an EC50 of 20 nM.

Nomenclature
C-C motif chemokine receptor 4
Available assay modes
Agonist, Inverse agonist, Antagonist, PAM, NAM
Panels
à la carte, Immunology/Infection, Oncology, Hematology, Respiratory, Gastrointestinal, Dermatology, Human non-orphan GPCRs

CCR4 orthologs in other animal species including rat, rabbit, dog, and macaque monkey are ready upon request.

Related Receptors