C-X3-C motif chemokine receptor 1 (CX3CR1)

Human CX3CR1

Figure. Concentration-dependent activation of CX3CR1 by CX3CL1

Reporter cells were transfected with either the expression plasmid for human C-X3-C motif chemokine receptor 1 (CX3CR1) or the mock plasmid and treated with various concentrations of CX3CL1. Data points shown are the mean ± SEM of an experiment (n = 3), and the curve is a fit to Hill equation with an EC50 of 1.8 nM.

Nomenclature: C-X3-C motif chemokine receptor 1
Available assay modes: Agonist, Inverse agonist, Antagonist, PAM, NAM
Panels: à la carte, Immunology/Infection, Hematology, Neurology, Ophthalmology, Cardiology, Respiratory, Gastrointestinal, Dermatology, Musculoskeletal, Urology/Reproduction, Human non-orphan GPCRs

CX3CR1 orthologs in other animal species including rat, rabbit, dog, and macaque monkey are ready upon request.

Related Receptors


Human	CCR1 C-C motif chemokine receptor 1
Human	CCR2 C-C motif chemokine receptor 2
Human	CCR4 C-C motif chemokine receptor 4
Human	CCR5 C-C motif chemokine receptor 5
Human	CCR6 C-C motif chemokine receptor 6
Human	CCR7 C-C motif chemokine receptor 7
Human	CCR8 C-C motif chemokine receptor 8
Human	CCR9 C-C motif chemokine receptor 9
Human	CCR10 C-C motif chemokine receptor 10
Human	CXCR1 C-X-C motif chemokine receptor 1
Human	CXCR2 C-X-C motif chemokine receptor 2
Human	CXCR3 C-X-C motif chemokine receptor 3
Human	CXCR4 C-X-C motif chemokine receptor 4
Human	CXCR5 C-X-C motif chemokine receptor 5
Human	CXCR6 C-X-C motif chemokine receptor 6
Human	XCR1 X-C motif chemokine receptor 1
Human	CX3CR1 C-X3-C motif chemokine receptor 1
Human	CCR3 C-C motif chemokine receptor 3
Mouse	Ccr1 chemokine (C-C motif) receptor 1
Mouse	Ccr4 chemokine (C-C motif) receptor 4
Mouse	Ccr5 chemokine (C-C motif) receptor 5
Mouse	Ccr6 chemokine (C-C motif) receptor 6
Mouse	Ccr7 chemokine (C-C motif) receptor 7
Mouse	Ccr8 chemokine (C-C motif) receptor 8
Mouse	Ccr9 chemokine (C-C motif) receptor 9
Mouse	Ccr10 chemokine (C-C motif) receptor 10
Mouse	Cxcr1 chemokine (C-X-C motif) receptor 1
Mouse	Cxcr2 chemokine (C-X-C motif) receptor 2
Mouse	Cxcr3 chemokine (C-X-C motif) receptor 3
Mouse	Cxcr4 chemokine (C-X-C motif) receptor 4
Mouse	Cxcr5 chemokine (C-X-C motif) receptor 5
Mouse	Cxcr6 chemokine (C-X-C motif) receptor 6
Mouse	Cx3cr1 chemokine (C-X3-C motif) receptor 1