Human C3AR1

Figure. Concentration-dependent activation of C3AR1 by C3a

Reporter cells were transfected with either the expression plasmid for human complement C3a receptor 1 (C3AR1) or the mock plasmid and treated with various concentrations of C3a. Data points shown are the mean ± SEM of an experiment (n = 3), and the curve is a fit to Hill equation with an EC50 of 3.7 nM.

Nomenclature
complement C3a receptor 1
Available assay modes
Agonist, Inverse agonist, Antagonist, PAM, NAM
Panels
à la carte, Respiratory, Human non-orphan GPCRs

C3AR1 orthologs in other animal species including rat, rabbit, dog, and macaque monkey are ready upon request.

Related Receptors

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