Human GPR174

Figure. Concentration-dependent activation of GPR174 by LPS

Reporter cells were transfected with either the expression plasmid for human G protein-coupled receptor 174 (GPR174) or the mock plasmid and treated with various concentrations of LPS. Data points shown are the mean ± SEM of an experiment (n = 3), and the curve is a fit to Hill equation with an EC50 of 22 nM.