Human S1PR1

Figure. Concentration-dependent activation of S1PR1 by S1P

Reporter cells were transfected with either the expression plasmid for human sphingosine-1-phosphate receptor 1 (S1PR1) or the mock plasmid and treated with various concentrations of S1P. Data points shown are the mean ± SEM of an experiment (n = 3), and the curve is a fit to Hill equation with an EC50 of 120 nM.

Nomenclature
sphingosine-1-phosphate receptor 1
Available assay modes
Agonist, Inverse agonist, Antagonist, PAM, NAM
Panels
à la carte, Oncology, Hematology, Human non-orphan GPCRs

S1PR1 orthologs in other animal species including rat, rabbit, dog, and macaque monkey are ready upon request.

Related Receptors

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