Human MC1R

Figure. Concentration-dependent activation of MC1R by α‐MSH

Reporter cells were transfected with either the expression plasmid for human melanocortin 1 receptor (MC1R) or the mock plasmid and treated with various concentrations of α‐MSH. Data points shown are the mean ± SEM of an experiment (n = 3), and the curve is a fit to Hill equation with an EC50 of 850 pM.

Nomenclature
melanocortin 1 receptor
Available assay modes
Agonist, Inverse agonist, Antagonist, PAM, NAM
Panels
à la carte, Oncology, Endocrinology/Metabolism, Neurology, Ophthalmology, Dermatology, Musculoskeletal, Human non-orphan GPCRs

MC1R orthologs in other animal species including rat, rabbit, dog, and macaque monkey are ready upon request.

Related Receptors

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