Human MC2R

Figure. Concentration-dependent activation of MC2R by ACTH

Reporter cells were transfected with either the expression plasmid for human melanocortin 2 receptor (MC2R) or the mock plasmid and treated with various concentrations of ACTH. Data points shown are the mean ± SEM of an experiment (n = 3), and the curve is a fit to Hill equation with an EC50 of 4.1 nM.

Nomenclature
melanocortin 2 receptor
Available assay modes
Agonist, Inverse agonist, Antagonist, PAM, NAM
Panels
à la carte, Immunology/Infection, Endocrinology/Metabolism, Musculoskeletal, Urology/Reproduction, Human non-orphan GPCRs

MC2R orthologs in other animal species including rat, rabbit, dog, and macaque monkey are ready upon request.

Related Receptors

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