Human MTNR1A

Figure. Concentration-dependent activation of MTNR1A by melatonin

Reporter cells were transfected with either the expression plasmid for human melatonin receptor 1A (MTNR1A) or the mock plasmid and treated with various concentrations of melatonin. Data points shown are the mean ± SEM of an experiment (n = 3), and the curve is a fit to Hill equation with an EC50 of 100 pM.