Human OPRM1

Figure. Concentration-dependent activation of OPRM1 by DAMGO

Reporter cells were transfected with either the expression plasmid for human opioid receptor mu 1 (OPRM1) or the mock plasmid and treated with various concentrations of DAMGO. Data points shown are the mean ± SEM of an experiment (n = 3), and the curve is a fit to Hill equation with an EC50 of 21 nM.

Nomenclature
opioid receptor mu 1
Available assay modes
Agonist, Inverse agonist, Antagonist, PAM, NAM
Panels
à la carte, Immunology/Infection, Hematology, Endocrinology/Metabolism, Psychiatry, Neurology, Cardiology, Respiratory, Gastrointestinal, Dermatology, Safety Premium, Safety, Human non-orphan GPCRs

OPRM1 orthologs in other animal species including rat, rabbit, dog, and macaque monkey are ready upon request.

Related Receptors