Human HCRTR2

Figure. Concentration-dependent activation of HCRTR2 by orexin A

Reporter cells were transfected with either the expression plasmid for human hypocretin receptor 2 (HCRTR2) or the mock plasmid and treated with various concentrations of orexin A. Data points shown are the mean ± SEM of an experiment (n = 3), and the curve is a fit to Hill equation with an EC50 of 3.0 nM.