G protein-coupled receptor 35 (GPR35)

Figure. Concentration-dependent activation of GPR35 by zaprinast

Reporter cells were transfected with either the expression plasmid for human G protein-coupled receptor 35 (GPR35) or the mock plasmid and treated with various concentrations of zaprinast. Data points shown are the mean ± SEM of an experiment (n = 3), and the curve is a fit to Hill equation with an EC50 of 2.8 µM.

Nomenclature: G protein-coupled receptor 35
Available assay modes: Agonist
Panels: à la carte, Human orphan GPCRs

GPR35 orthologs in other animal species including rat, rabbit, dog, and macaque monkey are ready upon request.

Related Receptors


Mouse	Ackr3 atypical chemokine receptor 3
Mouse	Gpr1 G protein-coupled receptor 1
Mouse	Gpr3 G-protein coupled receptor 3
Mouse	Gpr6 G protein-coupled receptor 6
Mouse	Gpr12 G-protein coupled receptor 12
Mouse	Gpr17 G protein-coupled receptor 17
Mouse	Gpr18 G protein-coupled receptor 18
Mouse	Gpr19 G protein-coupled receptor 19
Mouse	Gpr20 G protein-coupled receptor 20
Mouse	Gpr21 G protein-coupled receptor 21
Mouse	Gpr22 G protein-coupled receptor 22
Mouse	Gpr25 G protein-coupled receptor 25
Mouse	Gpr26 G protein-coupled receptor 26
Mouse	Gpr27 G protein-coupled receptor 27
Mouse	Gpr35 G protein-coupled receptor 35
Mouse	Gpr37 G protein-coupled receptor 37
Mouse	Gpr37l1 G protein-coupled receptor 37-like 1
Mouse	Gpr39 G protein-coupled receptor 39
Mouse	Gpr45 G protein-coupled receptor 45
Mouse	Gpr61 G protein-coupled receptor 61
Mouse	Gpr63 G protein-coupled receptor 63
Mouse	Gpr75 G protein-coupled receptor 75
Mouse	Gpr82 G protein-coupled receptor 82
Mouse	Gpr83 G protein-coupled receptor 83
Mouse	Gpr85 G protein-coupled receptor 85
Mouse	Gpr87 G protein-coupled receptor 87
Mouse	Gpr88 G-protein coupled receptor 88
Mouse	Gpr135 G protein-coupled receptor 135
Mouse	Gpr146 G protein-coupled receptor 146
Mouse	Gpr150 G protein-coupled receptor 150
Mouse	Gpr151 G protein-coupled receptor 151
Mouse	Gpr152 G protein-coupled receptor 152
Mouse	Gpr160 G protein-coupled receptor 160
Mouse	Gpr162 G protein-coupled receptor 162
Mouse	Gpr171 G protein-coupled receptor 171
Mouse	Gpr173 G-protein coupled receptor 173
Mouse	Gpr182 G protein-coupled receptor 182
Mouse	Lgr6 leucine-rich repeat-containing G protein-coupled receptor 6
Mouse	Mas1 MAS1 oncogene
Mouse	Mrgprd MAS-related GPR, member D
Mouse	Mrgpre MAS-related GPR, member E
Mouse	Mrgprf MAS-related GPR, member F
Mouse	Mrgprg MAS-related GPR, member G
Mouse	Mrgprx1 MAS-related GPR, member X1
Mouse	Taar2 trace amine-associated receptor 2
Mouse	Taar5 trace amine-associated receptor 5
Mouse	Taar6 trace amine-associated receptor 6
Mouse	Taar8a trace amine-associated receptor 8A
Mouse	Taar9 trace amine-associated receptor 9
Mouse	Gpr157 G protein-coupled receptor 157

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Human GPR35

Figure. Concentration-dependent activation of GPR35 by zaprinast

Related Receptors