Prolactin-releasing peptide receptor

Overview

The precursor (PRLH, P81277) for PrRP generates 31 and 20-amino-acid versions. QRFP43 (43RFa) (named after a pyroglutamylated arginine-phenylalanine-amide peptide) is a 43 amino acid peptide derived from ... [read more] href="https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:29982">QRFP (P83859) and is also known as P518 or 26RFa. RFRP is an RF amide-related peptide [1] derived from a FMRFamide-related peptide precursor (NPVF, Q9HCQ7), which is cleaved to generate neuropeptide SF, neuropeptide RFRP-1, neuropeptide RFRP-2 and neuropeptide RFRP-3 (neuropeptide NPVF).

Reference

Hinuma S, Shintani Y, Fukusumi S, et al. New neuropeptides containing carboxy-terminal RFamide and their receptor in mammals. Nat Cell Biol 2000;2:703-8.

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Human	PRLHR prolactin releasing hormone receptor
Mouse	Prlhr prolactin releasing hormone receptor

Human

PRLHR

prolactin releasing hormone receptor

Mouse

Prlhr

prolactin releasing hormone receptor

Species	Receptor	Family	Assays
Human	PRLHR prolactin releasing hormone receptor	Prolactin-releasing peptide receptor	Available Assay modes: Agonist ⋅ Inverse agonist ⋅ Antagonist ⋅ PAM ⋅ NAM Panels: Human non-orphan GPCRs ⋅ à la carte	Reference agonist: PrRp‐31 EC50: 1.8 nM
Mouse	Prlhr prolactin releasing hormone receptor	Prolactin-releasing peptide receptor	Available Assay modes: Agonist ⋅ Inverse agonist ⋅ Antagonist ⋅ PAM ⋅ NAM Panels: Mouse non-orphan GPCRs ⋅ à la carte	Reference agonist: PrRp‐31 EC50: 1.4 nM

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